Phagocyte Biology Laboratory

Dr. Bryan Heit, Western University

About Us

Welcome! You have reached the homepage of the laboratory of Dr. Bryan Heit. Our lab is part of the Department of Microbiology and Immunology at Western University, and we are members of the Center for Human Immunology, the lead centre for the CIHR Human Immunology Network.

Our interests surround the function of phagocytes – white blood cells which ingest (phagocytose) pathogens, particles, and dead cells. We focus on the cellular and molecular processes which control the function of these cells during the maintenance of homeostasis, during infection and during chronic inflammatory disease. Central to most of our studies is the study of efferoctyosis – the phagocytic removal of apoptotic (dying) cells, and how failures in this process lead to inflammation, autoimmunity and infection.

Lab News

New Paper Published!

Our second paper of 2015 is officially in press. The in-press version of the paper can be found here.

Pillon NJ, Azizi PM, Li YE, Liu J, Wang C, Chan KL, Hopperton KE, Bazinet RP,
Heit B, Bilan PJ, Lee WL, Klip A. Palmitate-induced inflammatory pathways in
human adipose microvascular endothelial cells promotes monocyte adhesion and
impairs insulin transcytosis. Am J Physiol Endocrinol Metab. 2015 May. PMID 25944880.

Meet the newest member of the Heit lab

Our newest lab member, Charles Yin, has going to be featured in the next edition of Current Affairs, Schulich School of Medicine and Dentistry’s training newsletter. You can get an early peak at his interview here.

Charles Yin, Image from Current Affairs

Congratulations Honours Students!


Honours Presentations 2015

Our honours students, Melanie and Yadin, completed their honours program yesterday with oral presentations of their work. Look for their contributions in our labs upcoming publications.




Congratulations Amanda and Jack!

Our graduate students Amanda Evans & Jack Blackburn recently presented abstracts at the Annual McGill Biomedical Graduate Conference, in Montreal Quebec. In addition, both Amanda and Jack won MNI Travel Awards to attend this conference.

Twitter Feed

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Upcoming Events

April 23, 2015
RGE Murray Seminar Series Presents: Dr. Gabriel Nunez University of Michigan

May 4, 2015
RGE Murray Seminar Series Presents: Dr. Amit Barr-Or McGill University.

May 7, 2015
RGE Murray Seminar Series Presents the Annual RGE Murray Lectureship: Dr. Rafi Ahmed Emory University

May 14, 2015
RGE Murray Seminar Series Presents: Dr. Patrick Venables University of Oxford

May 21 & 22, 2015
Microbiology & Immunology, ID and MedMicro Joint Retreat

May 31 - June 6, 2015
GRC Phagocyte Conference, Waterville Valley, NH

July 11-15, 2015
American Society for Virology Annual Conference Hosted here at the University of Western Ontario by our home department, the Department of Microbiology & Imunology

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